There are a lot of quality .22 pistols on the market today. I'm especially fond of the Browning Buckmark, but Ruger makes a nice rimfire too. Unfortunately, neither is inexpensive. Walther & Sig Sauer make models, but I've never been very impressed with them.
You might take a good long look at the Beretta Neos. It is a quality pistol that sells new for $225-275, depending on the configuration. If you can get over its space age looks then you might have a real winner.
I should add that I have shot examples of all of these pistols within the past few years. If I was buying one today, it'd be the Neos.