I agree with that bolded statement. My youngest daughter doesn't handle recoil well with anything other than a .22LR so if the SHTF she will be sporting either the Walterh P22 or the Sig522. My oldest can shoot .45acp and is fairly accurate. I have issue with people that are recoil sensitive when they go to .40S&W or to 9mm thinking the smaller the bullet the less its recoil should be. That assumption is wrong for those three calibers (and some others). Each recoil is different and I prefer the recoil of a .45acp over .40 or 9mm. The main concern is what gun are you shooting it out of with barrel lenght and weight of the gun coming into play. About the only caliber that I have shot that has minimal recoil is .22lr so I can recommend it to people that have severe limitations on what they can handle due to age (young or old) or other physical limitations. Is it the perfect round? Yes for them.
Capacity can be a big issue when choosing a caliber. Many choose 9mm or 40S&W over .45acp since they can typically have more rounds per magazine. My solution is to carry a 15+1 FNP-45 which meets my requirements of capacity while keeping my caliber choice. I had to agree that 20 rounds of 9mm sounded better than 8 rounds of .45acp so I started my capacity search. With .22LR guns I haven't seen many that offer magazines over 10 rounds for some reason. My Sig522 comes with 25 round magazines but the Walther P22 only has 10 rounders available. The Kelteck PMR is about the only higher capacity 22 (magnum) gun I have seen. So for a 22lr pistol I would say it is not the perfect gun based on capacity alone.
So all said and done, there are good arguments for and against every caliber. Each person has their own set of requirements, physical and desires. Anyone that makes me draw down on them should expect .45acp HST's arriving soon.
Indeed to both the above- but. I really think comparing .45/.22 is a very apple-vs.-oranges thing. My comparison is vs. the 2 other more-common carry rounds -9mm/.40 (which, in actual "street" shootings are very much alike-ineffective,at best, most of the time). The bore and weight/mass of the rounds (above 180 grains) just seems to have worked best from 1873 until present, whether firing round nose lead, fmj ,OR hollow-points. 9mm-bore rounds
can work ok, but only seem to really do so when they are pushed to magnum-level velocities (.357 SIG/.38 Super). But-when you begin doing that, you are getting into even HIGHER amounts of recoil, and higher pressures-sort of defeating the purpose to being able to hit well, and repeatedly.
That said, for the small rounds- .22/.25, when used within their limits, they can work great. I carry .25 as my BUG without hesitation. But-I have practiced exentsively with it enough. I put no small effort into making sure I can consistently place shots with it-rapid-fired,since it would be foolish to expect 1-shot or even 2-shot stops with rounds so small and light in weight. Also, one must make sure to try to aim for "soft" areas, as bones are likely to stop /deflect such small rounds, rather than be penetrated by them. Gut shots, etc. being the order of the day.
But, in my own tests around here, .25 auto has penetrated almost everything my .45s have, so go figure...
As far as "handling" or shooting well: I can see folks who are especially recoil-sensitive resorting to .22/.25/.32 -but 9mm/.40? just a completely backwards logic, there. I think a lot of folks go into shooting with a pre-disposed idea of .45 being "too much" before they've even bothered to try firing one.
As for capacity- unless you are in an area in which you anticipate facing multiple armed opponents on a regular basis, I just dont see the justification of going 9mm etc. vs. 45. You will be hard-pressed to find any accounts of anyone needing more than 2 hits with .45 (excluding multiple hits to extremities -hands, feet, etc.) to bring things to an end.