Cross draw has its pluses, comfort being one of them.
FIST Holsters http://www.fist-inc.com offers holsters designed with belt loops and straps, Kydex or leather, to be worn either OWB and IWB. You can order straight draw or raked, with or without a thumbbreak, in addition to other options.
Personally, about a 30 degree rake works well when carried in front of the hip; straight draw works well at 9 o'clock for the slender built person as a raked holster allows the butt to protrude forward.
Crossdraw also has its shortcomings. FWIW something which may very well solve your weight bearing problem is a pair of Perry Suspenders http://perrysuspenders.com. Try a pair, both styles, before switching to crossdraw with the GLOCK.
Also consider a lighter hogleg - something in the Kahr "P" series catagory.