There are replacement windows and sliding-glass doors made today that have a layer of polyethylene sandwiched between glass sheets exactly like a car windshield. Only thicker. It is for security, not safety like a car windshield.
I've seen a demonstration video where the actor had to beat and beat and beat on the sliding glass door with a bat to make decent hole in it. The glass cracked pretty quick, but creating a hole took a while. Something like that on the sliders and the bottom story windows might be useful.