Additionally, even when a less-than-optimal-design hollow point passes through a targeted body, it has likely shed more of it's energy while passing through than a full metal jacket "ball ammo" bullet would, increasing damage to the initial target and reducing damage to the anything beyond.
In addition, the chance of a bullet passing through a 132 pound person's torso is likely much greater than it passing through my biz partner's 320 pounds.
In shooting a lightweight, lightly clothed person, a Glaser Safety Slug would probably be ideal. In shooting a much larger, winter clothed target, one probably needs a more substantial round to get adequate penetration...
There is no perfect bullet.