I've come to the realization that putting your gun (if it's your carry weapon) in the same place every night is very important. I don't have a nightstand, or space for one, so I keep my Walther on my computer desk which is just a few feet away from my bed. Not only that, but I keep it in the same place in the same position every time so that I can just throw my hand on the desk and grab it.
If for whatever reason I don't want to go across the room, or need more firepower, I have my Ruger Blackhawk .357 sitting atop the washer/dryer in the closet next to my bed (a strange location, I know, but I have a strange floor plan).
Whenever I'm at home and not carrying them, these two weapons stay in the same place all the time, so that I can pick them up even if it's pitch black in the room. But to answer your question...well, I can't without knowing the layout of your home, the type of furniture you have, the position of your bed, etc. So you may end up having to store the weapon out of arms reach. I wouldn't say that's a terrible thing. First off, you'd be amazed at how ungroggy you can be immediately after waking up when you think you're in an emergency situation. Second, if you're in a situation in your own home where you don't have enough time to jump halfway across the room, you've probably been caught by surprise and have lost the battle before you even woke up.
I'm sure I'll take some flak for suggesting putting your HD weapon out of arm's reach, but I'd be willing to bet that I could be out of bed, over to my desk (less than 10' away), and weapon at the ready just ask quick as it would take someone to open a drawer. What's going to quicken your response more than anything is consistently keeping it in the same place every night and knowing exactly have to grab it in the dark. A gun in a familiar place across the room is going to be quicker to ready than a gun in an unfamiliar place under or next to your bed.
